Bicalutamide (CEP)

1.CAS RN: 90357-06-5

2.English Name:Bicalutimide

Chemical name: N-[4-Cyano-3-（trifluoromethyl）phenyl]-3-[（4-fluorophenyl）sulfonyl]-2-hydroxyl-2- methylpropanemide

Synonyms: Bicalutamide (Subject to patent free); 4-cyano-3-trifluoromethyl-N-(3-p-fluorophenylsulfonyl-2-hydroxy-2-methylpropionyl)aniline; N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methyl-propanamid; [(4- fluorophenyl) sulfonyl]-2-hydroxy- 2-methyl propanamide ; N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide; (2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide

3. Structural Formula:    

4. Molecular formula & molecular weight: C₁₈H₁₄F₄N₂O₄S  430.38

5. Characters: It’s a white or almost white crystal powder, odorless, tasteless, freely soluble in DMF; Soluble in butylene oxide; sparingly soluble in acetic ether and methanol; insoluble in water. 

6. Quality Standard: Enterprise standard :USP43

7. Usage: Prostate drug, It is developed by AstraZenca Internatioal,and it is the first antiandrogen non-corticosteroids drug for long-acting oral medication and firstly go on the market in 1995 in UK. An antiandrogen non-corticosteroids can be used treating prostate cancer in advanced stage as assistant drug, may also for treating prostate cancer in the early stage to play an important role.

8. Storage: It should be kept in room temperature, and away from light; stored in sealed containers.

9. Packing: paper bucket, 25kg/package.

10.Supply Ability: 800kg /month

11. HS CODE: 29309090.90

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